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less thanp>less than/p>less thandiv>POSTDOCTORAL SCHOLARRequisition # 3295Position Basicsless thanbr>less thanstrong>Advertising Ends on:less than/strong>less thanbr>Friday, June 5th, 2020less thanbr>less thanbr>less thanstrong>Advertising Started on:less than/strong>less thanbr>Friday, May 22nd, 2020less thanbr>less thanbr>less thanstrong>College:less than/strong>less thanbr>Carver College of Medicineless thanbr>less thanbr>less thanstrong>Department:less than/strong>less thanbr>Internal Medicineless thanbr>less thanbr>less thanbr>Salaryless thanbr>less thanstrong>Salary:less than/strong>less thanbr>$52,704.00 to Commensurateless thanbr>less thanbr>less thanbr>Position Detailsless thanbr>less thanstrong>Full/Part Time Status:less than/strong>less thanbr>Full Timeless thanbr>less thanbr>less thanstrong>Percent Time:less than/strong>less thanbr>100%less thanbr>less thanbr>less thanstrong>Position Description:less than/strong>less thanp>Lab of nutrient sensing in metabolic diseases aims to understand how lipid metabolite ceramides: impair nutrient sensing in adipose tissue and contribute to development of metabolic diseases such as obesity, diabetes, cardiovascular diseases etc. (Chaurasia et 2016, Cell Metabolism and Chaurasia et 2019, Science). The overreaching goal of one of the projects in the lab is to understand how adipocytes interact with immune cells to maintain adipocyte health. Using genetic and pharmacological tools to modulate ceramide accumulation immune regulatory cells less thanem>in vivoless than/em> combined with unbiased approaches we seek to understand how ceramide dependent nutrient sensing in immune-regulatory T-cells maintain adipocyte health. Therefore, we are currently seeking a postdoctoral candidate with strong background in immunology and/or metabolic diseases. We anticipate the start date to be 07/01/2020 or later. Successful applicants will be generously offered with NIH guideline-based salary and benefits and will be part of diabetes research community at University of Iowa Hospital and Clinics and affiliated Fraternal order of diabetes research institute. In addition to existing projects in the lab, he/she will be provided with sufficient support and freedom to ask new important questions and independently develop innovative research in the general context of laboratory interest.less than/p>less thanbr>less thanbr>less thanstrong>Education Requirement:less than/strong>less thanp>A recent PhD, MD, or MD/PhD degree (within 0-3 years) in physiology, biochemistry or related biomedical disciplines.less than/p>less thanbr>less thanbr>less thanstrong>Required Qualifications:less than/strong>less thanul>less thanbr>less thanli>less thanp>A strong research background in cell/molecular biology and biochemistry.less than/p>less than/li>less thanbr>less thanli>less thanp>Previous experience with mammalian cell culture, fluorescence microscopy, PCR, immunoblotting, and immunohistochemistry.less than/p>less than/li>less thanbr>less thanli>less thanp>A strong background in mouse genetics and phenotyping mouse models related to development if obesity and associated metabolic diseases.less than/p>less than/li>less thanbr>less thanli>less thanp>A strong background in immunology with strong interest in T-effector and regulatory T-cells.less than/p>less than/li>less thanbr>less thanli>less thanp>Obtaining and analyzing datasets from Next-generation Sequencing experiments (Sc-RNAseq, Chip-Seq etc)less than/p>less than/li>less thanbr>less thanli>less thanp>Experience and / or interest big data analysis and scripting languages (R, Python) to analyse - OMICS datasets.less than/p>less than/li>less thanbr>less thanli>less thanp>An open and positive mind that actively contributes to the infrastructure and the success of the newly established research team and the department at large.less than/p>less than/li>less thanbr>less thanli>less thanp>Formulate research questions, design and conduct experiments, and organize and ana